El Badawi S A, Goepfert H, Fletcher G H, Herson J, Oswald M J
Laryngoscope. 1982 Apr;92(4):357-64.
This is a review of 418 patients with cancer of the pyriform sinus who had complete treatment at University of Texas M. D. Anderson Hospital, treated over a 28-year time span. Treatment modalities used included radiation therapy, surgery, and planned combined treatment, primarily in the form of surgery and postoperative radiation therapy. Superficial lesions, with no impairment of laryngeal motility, are suitable for irradiation therapy planned for cure. (The policies of treatment have changed throughout the years). Analysis is made comparing the results of the larger groups of patients treated by surgery only, or surgery followed by postoperative radiation therapy. There is a significant lower incidence of failure above the clavicle in the combined treatment group, and a better 5-year survival. Rate of recurrences and the specific sites of failure above the clavicles are discussed, as well as the means of preventing such. The causes of death between 2 and 5 years are presented.
这是对418例梨状窝癌患者的回顾性研究，这些患者在德克萨斯大学MD安德森癌症中心接受了为期28年的完整治疗。所采用的治疗方式包括放射治疗、手术以及计划性联合治疗，主要形式为手术及术后放射治疗。对于喉运动无损害的浅表病变，适合采用根治性放射治疗。（多年来治疗策略有所变化）。对仅接受手术治疗或手术联合术后放射治疗的较大患者群体的结果进行了分析比较。联合治疗组锁骨上区失败发生率显著降低，5年生存率更高。讨论了锁骨上区的复发率及失败的具体部位，以及预防措施。还列出了2至5年的死亡原因。
