Balentine J D, Spector M
Ann Neurol. 1977 Dec;2(6):520-3. doi: 10.1002/ana.410020612.
Selective discrete intraaxoplasmic deposits of hydroxyapatite crystallites were observed in adult male rats subjected to experimental trauma to the lumbosacral spinal cord. Although previously unreported in spinal cord trauma, the presence of these deposits in minimally altered axons and during the early posttrauma period suggests that such selective calcification may be of more than secondary significance. In view of the current emphasis on cytotoxicity of calcium, especially in relation to axonal degeneration, an evaluation of the role of calcium in augmenting traumatic spinal cord necrosis is warranted.
在遭受腰骶部脊髓实验性创伤的成年雄性大鼠中，观察到了羟基磷灰石微晶的选择性离散轴质内沉积。尽管此前在脊髓创伤中未见报道，但这些沉积物存在于轻微改变的轴突中且在创伤后早期，这表明这种选择性钙化可能具有不止次要的意义。鉴于当前对钙的细胞毒性的重视，尤其是与轴突变性相关的方面，有必要评估钙在加重创伤性脊髓坏死中的作用。
