Olding-Stenkvist E, Forsgren M, Henley D, Kreuger A, Lundmark K M, Nilsson A, Wadell G
Scand J Infect Dis. 1982;14(1):1-4. doi: 10.3109/inf.1982.14.issue-1.01.
Measles encephalopathy during immunosuppression (MEI) occurs in patients with immunologic defects and is fatal. The course of the disease in 2 children, 4 and 5 years old, in the remission phase of acute lymphatic leukemia is presented. Diagnosis was possible, post-mortem, by recognition of measles virus antigen in brain tissue and in one patient by demonstration of intrathecal production of measles antibodies. Treatment with interferon did not improve the condition. Preventive measures primarily by early immunization of the childhood population against measles is stressed.
免疫抑制期间的麻疹脑病（MEI）发生于有免疫缺陷的患者，且具有致命性。本文介绍了2名4岁和5岁处于急性淋巴细胞白血病缓解期儿童的病程。通过死后在脑组织中识别麻疹病毒抗原以及在1例患者中证明鞘内产生麻疹抗体得以确诊。使用干扰素治疗并未改善病情。强调主要通过对儿童群体进行早期麻疹免疫接种来采取预防措施。
