Ide F, Kusuhara S, Onuma H, Miyake T, Umemura S
Acta Pathol Jpn. 1982 Jan;32(1):135-42. doi: 10.1111/j.1440-1827.1982.tb02034.x.
An unusual case of a 37-year-old female with xanthomatous bone tumor of the right molar area of the mandible was presented. The tumor was asymptomatic and found to be a well-demarcated intraosseous radiolucent lesion on radiographic examination. Histologically the tumor consisted of two cell types, fibroblastic and xanthomatous cells. There was no osteoid, bone or cartilage formation. However, numerous psammomatous calcified bodies were seen in the fibrous area. Ultrastructural study showed fibroblastic cells in different stages of proliferation as the basis of the tumor which transform itself into xanthomatous cells. From the clinicopathologic findings, our case was thought to be a xanthic variant of non-ossifying fibroma (so-called xanthofibroma) of the mandible.
本文报告了一例37岁女性下颌右磨牙区黄色瘤性骨肿瘤的罕见病例。该肿瘤无症状，影像学检查发现为边界清晰的骨内透光性病变。组织学上，肿瘤由两种细胞类型组成，即成纤维细胞和黄色瘤细胞。未见类骨质、骨或软骨形成。然而，在纤维区域可见大量砂粒体样钙化小体。超微结构研究显示，处于不同增殖阶段的成纤维细胞是肿瘤的基础，这些细胞可转化为黄色瘤细胞。根据临床病理表现，我们认为该病例为下颌骨非骨化性纤维瘤（所谓的黄色纤维瘤）的黄色变体。
