Roessner A, Immenkamp M, Weidner A, Hobik H P, Grundmann E
J Cancer Res Clin Oncol. 1981;101(2):191-202. doi: 10.1007/BF00413313.
Case report of a patient with an unusual, rapidly growing bone tumor in the third and fourth cervical vertebrae. Histological and electron-microscopic investigations reveal a tumor composed of histiocytic cells, xanthomatous cells, giant cells of Touton type, and fibroblastic cells. No cellular features of malignancy are observed. From its cytologic appearance the tumor has to be classified as a benign fibrous histiocytoma. Regarding its ultrastructural features, the tumor may not be distinguished from non-ossifying fibroma of bone, but its clinical pattern shows obvious differences of localization and growth potential. the term "benign fibrous histiocytoma of bone" is proposed for these tumors which must be differentiated from non-ossifying fibroma.
一名第三和第四颈椎出现罕见的快速生长骨肿瘤患者的病例报告。组织学和电子显微镜检查显示肿瘤由组织细胞、黄色瘤细胞、Touton型巨细胞和成纤维细胞组成。未观察到恶性细胞特征。根据其细胞学表现,该肿瘤必须归类为良性纤维组织细胞瘤。就其超微结构特征而言,该肿瘤与骨的非骨化性纤维瘤无法区分,但其临床模式在定位和生长潜力方面存在明显差异。对于这些必须与非骨化性纤维瘤相鉴别的肿瘤,建议使用“骨良性纤维组织细胞瘤”这一术语。