给先天性风疹婴儿使用α干扰素。
Alpha interferon administration to infants with congenital rubella.
作者信息
Arvin A M, Schmidt N J, Cantell K, Merigan T C
出版信息
Antimicrob Agents Chemother. 1982 Feb;21(2):259-61. doi: 10.1128/AAC.21.2.259.
Abstract
Three infants with congenital rubella syndrome were given human leukocyte (alpha) interferon at doses of 2 x 10(5) to 7 X 10(5) U/kg per day for 10 days. A transient decrease in pharyngeal virus excretion was observed with treatment. No significant side effects were associated with the administration of human leukocyte interferon to these infants.
摘要
三名先天性风疹综合征婴儿接受了人白细胞（α）干扰素治疗，剂量为每天2×10⁵至7×10⁵单位/千克，持续10天。治疗期间观察到咽部病毒排泄有短暂减少。对这些婴儿给予人白细胞干扰素未发现明显副作用。
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本文引用的文献
1
Inhibition of rubella virus-specific RNA synthesis by interferon.
Proc Soc Exp Biol Med. 1971 Feb;136(2):615-8. doi: 10.3181/00379727-136-35324.
2
Interferon in congenital rubella: response to live attenuated measles vaccine.
J Immunol. 1967 Oct;99(4):771-7.
3
Clinical manifestations of postnatal and congenital rubella.
Arch Ophthalmol. 1967 Apr;77(4):434-9. doi: 10.1001/archopht.1967.00980020436004.
4
Administration of interferon to an infant with congenital rubella syndrome involving persistent viremia and cutaneous vasculitis.
Acta Paediatr Scand. 1976 Jan;65(1):105-10. doi: 10.1111/j.1651-2227.1976.tb04415.x.
5
Congenital rubella.
J Pediatr. 1975 Dec;87(6 Pt 2):1078-86. doi: 10.1016/s0022-3476(75)80119-3.
6
Comparison of immunofluorescence and immunoperoxidase staining for identification of rubella virus isolates.
J Clin Microbiol. 1978 Jun;7(6):576-83. doi: 10.1128/jcm.7.6.576-583.1978.
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