Faulkner R S, Gough D A
Can Med Assoc J. 1976 Jan 24;114(2):115-9.
An epidemic of rubella reached its peak in the Atlantic provinces in 1974, subsiding in early 1975. With the exception of Quebec the remainder of Canada showed a reverse trend, with a large increase in the numbers of cases reported in the first 41/2 months of 1975. The Halifax virus laboratory reported 106 serologically proven cases of rubella in 1974, 44 of them in pregnant women. In the aftermath of the epidemic many infants were born with the congenital rubella syndrome (CRS). A study carried out from Sept. 1, 1974 through Apr. 30, 1975 showed an 80% correlation between clinical diagnosis and the presence of rubella-specific IgM antibodies in 35 of these infants. Of the 23 infants in whom the diagnosis of CRS was made by laboratory or clinical findings or both, laboratory criteria were met in 20 (87.0%), clinical criteria in 19 (82.6%) and both laboratory and clinical criteria in 16 (69.6%).
风疹疫情于1974年在大西洋省份达到高峰，并于1975年初消退。除魁北克省外，加拿大其他地区呈现相反趋势，1975年头4个半月报告的病例数大幅增加。哈利法克斯病毒实验室报告称，1974年有106例血清学确诊的风疹病例，其中44例为孕妇。疫情过后，许多婴儿出生时患有先天性风疹综合征（CRS）。1974年9月1日至1975年4月30日进行的一项研究表明，在这些婴儿中，35例的临床诊断与风疹特异性IgM抗体的存在之间存在80%的相关性。在23例通过实验室检查或临床检查或两者确诊为CRS的婴儿中，20例（87.0%）符合实验室标准，19例（82.6%）符合临床标准，16例（69.6%）同时符合实验室和临床标准。
