自然杀伤细胞在病毒感染中的激活及作用
Activation and role of natural killer cells in virus infections.
作者信息
Biron C A, Welsh R M
出版信息
Med Microbiol Immunol. 1982;170(3):155-72. doi: 10.1007/BF02298196.
PMID:6176843
Abstract
Natural killer cells may play a significant role in virus infections. Virus-induced interferon activates these cells to become highly cytotoxic, and viral infections may also affect the proliferation of such cells. Non-immune mice have an apparently cellular defense mechanism which rapidly lyses implanted virus-infected cells. The evidence for NK cell involvement in viral disease is reviewed.
摘要
自然杀伤细胞可能在病毒感染中发挥重要作用。病毒诱导的干扰素激活这些细胞，使其具有高度细胞毒性，并且病毒感染也可能影响此类细胞的增殖。非免疫小鼠具有一种明显的细胞防御机制，可迅速裂解植入的病毒感染细胞。本文综述了自然杀伤细胞参与病毒性疾病的证据。
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