特应性皮炎中的自然杀伤细胞活性。
Natural killer cell activity in atopic dermatitis.
作者信息
Viander M, Uksila J, Lassila O, Jansén C T
出版信息
Arch Dermatol Res. 1982;274(3-4):283-8. doi: 10.1007/BF00403731.
PMID:6299206
Abstract
Natural killer (NK) cell activity against K562 cells was studied in 12 male adults with atopic dermatitis (AD). In a 4-h chromium release microcytotoxicity assay normal NK cell function and its augmentation by interferon (IFN-alpha) were observed in AD patients. Slightly higher NK cell activity was observed in patients with allergic respiratory symptoms. The role of NK cells in the pathogenesis of atopic dermatitis is discussed.
摘要
对12名患有特应性皮炎（AD）的成年男性进行了针对K562细胞的自然杀伤（NK）细胞活性研究。在4小时的铬释放微量细胞毒性试验中，观察到AD患者的NK细胞功能正常及其通过干扰素（IFN-α）的增强。在有过敏性呼吸道症状的患者中观察到NK细胞活性略高。本文讨论了NK细胞在特应性皮炎发病机制中的作用。
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