Swanston D W, Gleadle R I, Colgrave H F, Marrs T C
Toxicol Lett. 1982 Jan;10(1):87-90. doi: 10.1016/0378-4274(82)90272-7.
Dimethylsulphoxide (DMSO) induced swelling in guinea pig ears was found to be abolished by H1- and H2-receptor blocking agents. On histological examination of the ears some degranulation of mast cells was seen. It was concluded that the swelling was mediated by histamine release.
发现二甲基亚砜（DMSO）诱导的豚鼠耳部肿胀可被H1和H2受体阻断剂消除。对耳部进行组织学检查时，可见一些肥大细胞脱颗粒。得出的结论是，肿胀是由组胺释放介导的。
