Edmonds-Seal J, Turner A, Khodadadeh S, Bader D L, Fuller D J
Anaesthesia. 1982 Feb;37(2):147-51. doi: 10.1111/j.1365-2044.1982.tb01055.x.
Eighteen patients with unilateral osteoarthrosis of the hip were investigated in a trial which involved the injection of nine with bupivacaine and nine with normal saline. All the patients completed daily pain analogue charts. Their pain, mobility and functional activity were assessed and gait characteristics analysed, once before the injection and then at three monthly intervals. All the patients recorded a decrease in pain level within two weeks of injection, but it subsequently rose to pre-injection levels. There were no other significant general improvements after the injection. A significant increase in the maximum force at toe-off for the good leg was recorded one month after the injection. However, no further significant differences were found in the gait performance of either group of patients throughout the study. It is concluded that the hip nerve regional blockade offers no useful relief to the pain of osteoarthrosis of the hip joint.
在一项试验中，对18名单侧髋关节骨关节炎患者进行了研究，其中9人注射布比卡因，9人注射生理盐水。所有患者都填写了每日疼痛模拟量表。在注射前、注射后每隔三个月对他们的疼痛、活动能力和功能活动进行评估，并分析步态特征。所有患者在注射后两周内疼痛程度均有所下降，但随后又回升至注射前水平。注射后没有其他显著的总体改善。注射后一个月，健侧足趾离地时的最大力量显著增加。然而，在整个研究过程中，两组患者的步态表现均未发现进一步的显著差异。结论是，髋关节神经区域阻滞对髋关节骨关节炎疼痛没有有效的缓解作用。
