粗糙脉孢菌am位点的突变。
Mutation at the am locus of Neurospora crassa.
作者信息
Kinsey J A, Hung B S
出版信息
Genetics. 1981 Nov-Dec;99(3-4):405-14. doi: 10.1093/genetics/99.3-4.405.
Abstract
Forty-eight new mutations at the am locus of Neurospora crassa have been characterized. Nineteen mutations were induced by UV; of these, eight were missense, two were frameshifts, two were nonsense, three were deletions and four were unidentified. Twenty-nine mutations were induced with nitrous acid; of these, twenty-one were missense, three were frameshifts, one was nonsense, two were deletions and one was genetically unstable.
摘要
已对粗糙脉孢菌am位点的48个新突变进行了表征。19个突变由紫外线诱导产生；其中，8个为错义突变，2个为移码突变，2个为无义突变，3个为缺失突变，4个未鉴定。29个突变由亚硝酸诱导产生；其中，21个为错义突变，3个为移码突变，1个为无义突变，2个为缺失突变，1个遗传不稳定。
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1
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J Mol Biol. 1966 Jun;17(2):503-12. doi: 10.1016/s0022-2836(66)80160-2.
2
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Genet Res. 1966 Feb;7(1):18-31. doi: 10.1017/s0016672300009447.
3
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Aust J Biol Sci. 1973 Dec;26(6):1355-70. doi: 10.1071/bi9731355.
4
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6
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7
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8
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