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相似文献

1
Mutation at the am locus of Neurospora crassa.粗糙脉孢菌am位点的突变。
Genetics. 1981 Nov-Dec;99(3-4):405-14. doi: 10.1093/genetics/99.3-4.405.
2
Sequencing studies of ICR-170 mutagenic specificity in the am (NADP-specific glutamate dehydrogenase) gene of Neurospora crassa.粗糙脉孢菌am(NADP特异性谷氨酸脱氢酶)基因中ICR - 170诱变特异性的测序研究。
Genetics. 1986 May;113(1):45-51. doi: 10.1093/genetics/113.1.45.
3
An unstable allele of the am locus of Neurospora crassa.粗糙脉孢菌am基因座的一个不稳定等位基因。
Genetics. 1979 Nov;93(3):577-86. doi: 10.1093/genetics/93.3.577.
4
The Neurospora am gene and allelic complementation.粗糙脉孢菌am基因与等位基因互补。
Bioessays. 1988 Nov;9(5):169-72. doi: 10.1002/bies.950090508.
5
Transformation of Neurospora crassa with the cloned am (glutamate dehydrogenase) gene.用克隆的am(谷氨酸脱氢酶)基因转化粗糙脉孢菌。
Mol Cell Biol. 1984 Jan;4(1):117-22. doi: 10.1128/mcb.4.1.117-122.1984.
6
Frameshift mutations affecting the N-terminal sequence of Neurospora NADP-specific glutamate dehydrogenase.影响粗糙脉孢菌NADP特异性谷氨酸脱氢酶N端序列的移码突变。
J Mol Biol. 1980 Feb 25;137(2):125-35. doi: 10.1016/0022-2836(80)90320-4.
7
Hydroxylamine-induced purple mutants (ad-3) in Neurospora crassa. II. Identification of genetic alteration at the molecular level.羟胺诱导的粗糙脉孢菌紫色突变体(ad-3)。II. 分子水平上遗传改变的鉴定。
Hereditas. 1971;68(2):219-34. doi: 10.1111/j.1601-5223.1971.tb02398.x.
8
Mutagenesis at the ad-3A and ad-3B loci in haploid UV-sensitive strains of Neurospora crassa. VI. Genetic characterization of ad-3 mutants provides evidence for qualitative differences in the spectrum of genetic alterations between wild-type and nucleotide excision-repair-deficient strains.粗糙脉孢菌单倍体紫外线敏感菌株中ad - 3A和ad - 3B位点的诱变。VI. ad - 3突变体的遗传特征为野生型和核苷酸切除修复缺陷型菌株之间遗传改变谱的定性差异提供了证据。
Mutat Res. 1983 Mar;108(1-3):93-108. doi: 10.1016/0027-5107(83)90112-4.
9
Mutagenesis at the ad-3A and ad-3B loci in haploid UV-sensitive strains of Neurospora crassa. IV. Comparison of dose-response curves for MNNG, 4NQO and ICR-170 induced inactivation and mutation-induction.粗糙脉孢菌单倍体紫外线敏感菌株中ad-3A和ad-3B位点的诱变。IV. 甲基硝基亚硝基胍、4-硝基喹啉-1-氧化物和ICR-170诱导的失活和诱变的剂量反应曲线比较。
Mutat Res. 1981 Jan;80(1):27-41. doi: 10.1016/0027-5107(81)90175-5.
10
Nucleotide sequence and nuclear protein binding of the two regulatory sequences upstream of the am (GDH) gene in Neurospora.粗糙脉孢菌中am(GDH)基因上游两个调控序列的核苷酸序列及核蛋白结合情况
Mol Gen Genet. 1990 Apr;221(2):148-54. doi: 10.1007/BF00261714.

引用本文的文献

1
Epigenetic control of a transposon-inactivated gene in Neurospora is dependent on DNA methylation.粗糙脉孢菌中转座子失活基因的表观遗传调控依赖于DNA甲基化。
Genetics. 1996 May;143(1):137-46. doi: 10.1093/genetics/143.1.137.
2
A targeted-replacement system for identification of signals for de novo methylation in Neurospora crassa.一种用于鉴定粗糙脉孢菌中从头甲基化信号的靶向替换系统。
Mol Cell Biol. 1994 Nov;14(11):7059-67. doi: 10.1128/mcb.14.11.7059-7067.1994.
3
Nitrogen source regulates glutamate dehydrogenase NADP synthesis in Neurospora crassa.氮源调节粗糙脉孢菌中谷氨酸脱氢酶NADP的合成。
J Bacteriol. 1983 Apr;154(1):524-8. doi: 10.1128/jb.154.1.524-528.1983.
4
Chromosomal loci of Neurospora crassa.粗糙脉孢菌的染色体位点。
Microbiol Rev. 1982 Dec;46(4):426-570. doi: 10.1128/mr.46.4.426-570.1982.
5
Transformation of Neurospora crassa with recombinant plasmids containing the cloned glutamate dehydrogenase (am) gene: evidence for autonomous replication of the transforming plasmid.用含有克隆的谷氨酸脱氢酶(am)基因的重组质粒转化粗糙脉孢菌:转化质粒自主复制的证据。
Mol Cell Biol. 1984 Oct;4(10):2041-51. doi: 10.1128/mcb.4.10.2041-2051.1984.
6
Oxidation of Neurospora crassa NADP-specific glutamate dehydrogenase by activated oxygen species.活性氧对粗糙脉孢菌NADP特异性谷氨酸脱氢酶的氧化作用。
J Bacteriol. 1989 Nov;171(11):6243-50. doi: 10.1128/jb.171.11.6243-6250.1989.
7
Efficient DNA pairing in a Neurospora mutant defective in chromosome pairing.在染色体配对存在缺陷的粗糙脉孢菌突变体中高效的DNA配对
Mol Gen Genet. 1991 Dec;231(1):49-52. doi: 10.1007/BF00293820.
8
Specificity of repeat-induced point mutation (RIP) in Neurospora: sensitivity of non-Neurospora sequences, a natural diverged tandem duplication, and unique DNA adjacent to a duplicated region.粗糙脉孢菌中重复序列诱导点突变(RIP)的特异性:非粗糙脉孢菌序列的敏感性、自然分化的串联重复以及与重复区域相邻的独特DNA。
Genetics. 1991 Apr;127(4):711-7. doi: 10.1093/genetics/127.4.711.
9
Recurrence of repeat-induced point mutation (RIP) in Neurospora crassa.粗糙脉孢菌中重复诱导点突变(RIP)的复发。
Genetics. 1991 Apr;127(4):699-710. doi: 10.1093/genetics/127.4.699.

本文引用的文献

1
Multiple active varieties of Neurospora glutamate dehydrogenase formed by hybridization between two inactive mutant proteins in vivo and in vitro.通过体内和体外两种无活性突变蛋白杂交形成的多个活性神经孢霉谷氨酸脱氢酶变体。
J Mol Biol. 1966 Jun;17(2):503-12. doi: 10.1016/s0022-2836(66)80160-2.
2
Glutamic dehydrogenase in revertants of am mutants in Neurospora.粗糙脉孢菌am突变体回复突变体中的谷氨酸脱氢酶
Genet Res. 1966 Feb;7(1):18-31. doi: 10.1017/s0016672300009447.
3
A new map of the amination-1 locus of Neurospora crassa, and the effect of the recombination-3 gene.粗糙脉孢菌胺化-1基因座的新图谱以及重组-3基因的作用。
Aust J Biol Sci. 1973 Dec;26(6):1355-70. doi: 10.1071/bi9731355.
4
Amino-acid sequence of NADP-specific glutamate dehydrogenase of neurospora crassa.粗糙脉孢菌NADP特异性谷氨酸脱氢酶的氨基酸序列。
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4361-5. doi: 10.1073/pnas.71.11.4361.
5
Positive selection of mutants with deletions of the gal-chl region of the Salmonella chromosome as a screening procedure for mutagens that cause deletions.对沙门氏菌染色体gal-chl区域缺失的突变体进行正向选择,以此作为一种筛选导致缺失的诱变剂的程序。
J Bacteriol. 1975 Jan;121(1):259-66. doi: 10.1128/jb.121.1.259-266.1975.
6
Direct selective procedure for isolating Neurospora mutants defective in nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase.用于分离烟酰胺腺嘌呤二核苷酸磷酸特异性谷氨酸脱氢酶缺陷型脉孢菌突变体的直接选择程序。
J Bacteriol. 1977 Dec;132(3):751-6. doi: 10.1128/jb.132.3.751-756.1977.
7
The molecular basis of an osmotically reparable mutant of Neurospora crassa producing unstable glutamate dehydrogenase.粗糙脉孢菌产生不稳定谷氨酸脱氢酶的渗透可修复突变体的分子基础。
J Mol Biol. 1977 Mar 15;110(4):627-42. doi: 10.1016/s0022-2836(77)80081-8.
8
Frameshifts and frameshift suppressors in Saccharomyces cerevisiae.酿酒酵母中的移码突变和移码抑制因子
Genetics. 1977 Aug;86(4):745-64. doi: 10.1093/genetics/86.4.745.

粗糙脉孢菌am位点的突变。

Mutation at the am locus of Neurospora crassa.

作者信息

Kinsey J A, Hung B S

出版信息

Genetics. 1981 Nov-Dec;99(3-4):405-14. doi: 10.1093/genetics/99.3-4.405.

DOI:10.1093/genetics/99.3-4.405
PMID:6177580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1214510/
Abstract

Forty-eight new mutations at the am locus of Neurospora crassa have been characterized. Nineteen mutations were induced by UV; of these, eight were missense, two were frameshifts, two were nonsense, three were deletions and four were unidentified. Twenty-nine mutations were induced with nitrous acid; of these, twenty-one were missense, three were frameshifts, one was nonsense, two were deletions and one was genetically unstable.

摘要

已对粗糙脉孢菌am位点的48个新突变进行了表征。19个突变由紫外线诱导产生;其中,8个为错义突变,2个为移码突变,2个为无义突变,3个为缺失突变,4个未鉴定。29个突变由亚硝酸诱导产生;其中,21个为错义突变,3个为移码突变,1个为无义突变,2个为缺失突变,1个遗传不稳定。