Johnson J P, Meo T, Riethmüller G, Schendel D J, Wank R
J Exp Med. 1982 Jul 1;156(1):104-11. doi: 10.1084/jem.156.1.104.
A murine monoclonal antibody directed against a human B cell surface antigen with the characteristics of HLA-DR is described. The antigen detected is tightly linked to HLA and is correlated with the alloantigen HLA-Dw/DR3. Reactivity with a fraction of Dw/DRw6 cells is also observed. The determinant recognized by this antibody has been shown to be present on the smaller molecular weight beta subunit of the HLA-DR antigen.
描述了一种针对具有HLA - DR特征的人B细胞表面抗原的鼠单克隆抗体。所检测到的抗原与HLA紧密连锁,并与同种异体抗原HLA - Dw/DR3相关。也观察到该抗体与一部分Dw/DRw6细胞有反应性。已证明该抗体识别的决定簇存在于HLA - DR抗原分子量较小的β亚基上。