McBride J S, Walliker D, Morgan G
Science. 1982 Jul 16;217(4556):254-7. doi: 10.1126/science.6178159.
Monoclonal antibodies against blood forms of Plasmodium falciparum were used to demonstrate considerable antigenic diversity in this species. Different isolates were distinguished by their ability to react with certain antibodies, and most of the antibodies reacted specifically with merozoites, schizonts, or both. The distribution of different antigenic types appeared not to be related to geographic origin. Serological typing with monoclonal antibodies extends the range of methods for identification of different strains of this malaria parasite.
针对恶性疟原虫血液形态的单克隆抗体被用于证明该物种中存在相当大的抗原多样性。不同的分离株通过它们与某些抗体反应的能力来区分，并且大多数抗体与裂殖子、裂殖体或两者都发生特异性反应。不同抗原类型的分布似乎与地理起源无关。用单克隆抗体进行血清学分型扩展了鉴定这种疟原虫不同菌株的方法范围。
