外源性干扰素在腺病毒角膜结膜炎中的价值。初步结果。
The value of exogenous interferon in adenovirus keratoconjunctivitis. Preliminary results.
作者信息
Sundmacher R, Wigand R, Cantell K
出版信息
Graefes Arch Clin Exp Ophthalmol. 1982;218(3):139-40. doi: 10.1007/BF02215650.
PMID:6178649
Abstract
Fourteen patients with confirmed adenovirus (kerato-) conjunctivitis were treated at random with either exogenous interferon alpha (Le) (3 x 10(6) IU/ml, 1 drop daily) or with albumin. We observed no clinically relevant therapeutic effects. However, interferon seemed to exert a prophylactic effect on uninflamed fellow eyes. The prophylactic potency of interferon in adenovirus (kerato-)conjunctivitis should be evaluated in further controlled trials.
摘要
14例确诊为腺病毒（角膜）结膜炎的患者被随机分为两组，分别接受外源性干扰素α（Le）（3×10⁶IU/ml，每日1滴）或白蛋白治疗。我们未观察到临床相关的治疗效果。然而，干扰素似乎对未发炎的对侧眼有预防作用。干扰素在腺病毒（角膜）结膜炎中的预防效力应在进一步的对照试验中进行评估。
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