Whitehurst G B, Mashburn J P, Pretlow T G, Bradley E L, Boohaker E A
Cancer Res. 1982 Oct;42(10):4300-3.
Hexosaminidase activity in prostatic tissue has been compared in 15 patients with benign prostatic hyperplasia and 15 patients with prostatic carcinoma. The ratio of enzymatic activity for the two substrates tested (p-nitrophenyl-2-acetamido-2-deoxy-beta-D-glucopyranoside and p-nitrophenyl-2-acetamido-2-deoxy-beta-D-galactopyranoside) was not significantly different in the two groups of patients. The proportion of hexosaminidase represented by the B isozyme was not significantly different for the two groups of patients. Prostatic tissue hexosaminidase was greater (p = 0.0141) in carcinomatous prostates than in hyperplastic prostates.
对15例良性前列腺增生患者和15例前列腺癌患者的前列腺组织中的己糖胺酶活性进行了比较。在两组患者中，所测试的两种底物（对硝基苯基-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖苷和对硝基苯基-2-乙酰氨基-2-脱氧-β-D-吡喃半乳糖苷）的酶活性比率无显著差异。两组患者中由B同工酶代表的己糖胺酶比例无显著差异。癌性前列腺中的前列腺组织己糖胺酶活性高于增生性前列腺（p = 0.0141）。
