Blomgren H, Einhorn S, Von Stedingk L V, Wasserman J
J Interferon Res. 1981;1(4):513-9. doi: 10.1089/jir.1981.1.513.
Various interferon (INF) preparations were examined for their capacity to influence the poke weed mitogen (PWM) induced release of IgM and IgG by human lymphocytes in vitro. Variable results were obtained when partially purified preparations of leukocyte IFN-alpha were added at the beginning of the culture period: In some experiments Ig production increased and in others it decreased. The addition of a pure preparation of IFN-beta significantly augmented Ig release. It is suggested that substances other then IFN in impure IFN preparations may interfere with the PWM triggered Ig-release.
对多种干扰素（INF）制剂进行了检测，以考察其在体外影响人淋巴细胞经商陆有丝分裂原（PWM）诱导释放IgM和IgG的能力。在培养期开始时加入部分纯化的白细胞IFN-α制剂，结果各不相同：在一些实验中Ig产量增加，而在另一些实验中则减少。加入纯化的IFN-β制剂可显著增强Ig的释放。提示不纯的IFN制剂中除IFN外的其他物质可能会干扰PWM触发的Ig释放。
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