β-血小板球蛋白与血小板计数——恶性肿瘤、感染、年龄及肥胖的影响

Beta-thromboglobulin and platelet counts - effect of malignancy, infection, age and obesity.

作者信息

Douglas J T, Lowe G D, Forbes C D, Prentice C R

出版信息

Thromb Res. 1982 Mar 15;25(6):459-64. doi: 10.1016/0049-3848(82)90087-1.

Abstract

Plasma levels of beta-thromboglobulin (BTG) and platelet count were studied in 69 control subjects, 19 patients with operable abdominal malignancy, and 9 patients with acute bacterial infection. In control subjects there was a significant rise in BTG and fall in platelet count with age, and a negative correlation of BTG with obesity. BTG and platelet count were normal in patients with operable malignancy, but significantly increased in patients with acute bacterial infection. These effects must be considered in studies of BTG and thrombosis.

摘要

对69名对照受试者、19名可手术腹部恶性肿瘤患者和9名急性细菌感染患者的血浆β-血小板球蛋白（BTG）水平和血小板计数进行了研究。在对照受试者中，BTG随年龄显著升高，血小板计数随年龄显著下降，且BTG与肥胖呈负相关。可手术恶性肿瘤患者的BTG和血小板计数正常，但急性细菌感染患者的BTG和血小板计数显著升高。在BTG与血栓形成的研究中必须考虑这些影响。