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Characterization, origin and evolution of alpha-fetoprotein and albumin in postnatal rat brain.

作者信息

Piñeiro A, Calvo M, Iguaz F, Lampreave F, Naval J

出版信息

Int J Biochem. 1982;14(9):817-23. doi: 10.1016/0020-711x(82)90103-3.

DOI:10.1016/0020-711x(82)90103-3
PMID:6182041
Abstract
  1. The levels of AFP and albumin in rat brain at birth were 77 and 340 micrograms per g of tissue, respectively. These levels quickly dropped with age. AFP was undetectable in 20 days brain extracts whereas 30 micrograms of albumin per g of brain were still measured. 2. AFP from brain and serum were identical by immunodiffusion, electrophoresis and immuno-affinoelectrophoresis with free Concanavalin A. 3. No in vitro synthesis of AFP and albumin in the postnatal brain was observed. However, the total amount of AFP in the developing rat brain increases from birth to 4-5 days post-partum.
摘要

相似文献

1
Characterization, origin and evolution of alpha-fetoprotein and albumin in postnatal rat brain.
Int J Biochem. 1982;14(9):817-23. doi: 10.1016/0020-711x(82)90103-3.
2
Changes in alpha-fetoprotein and albumin synthesis rates and their levels during fetal and neonatal development of rat brain.大鼠脑胎儿期和新生儿期发育过程中甲胎蛋白和白蛋白合成率及其水平的变化。
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Synthesis and secretion of alpha-fetoprotein and albumin by newborn rat brain cells in culture.新生大鼠脑细胞在培养条件下甲胎蛋白和白蛋白的合成与分泌
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Thyroxine-induced changes in the glycosylation pattern and in brain and serum levels of rat alpha-fetoprotein.甲状腺素诱导的大鼠甲胎蛋白糖基化模式、脑和血清水平的变化。
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[Fixation of polyunsaturated fatty acids by alpha fetoprotein and serum albumin in rats. Comparison with the accumulation of these acids in developing rat brain].[大鼠中α-甲胎蛋白和血清白蛋白对多不饱和脂肪酸的固定作用。与发育中大鼠大脑中这些脂肪酸的积累情况比较]
C R Seances Acad Sci D. 1979 Nov 26;289(14):1053-6.
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Origin of corticosteroid-binding globulin in fetal rat. Comparative dynamics of corticosteroid-binding globulin, alpha-fetoprotein, and albumin secretion in primary cultures of fetal rat hepatocytes.
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Alpha-fetoprotein (AFP) modulates the effect of serum albumin on brain development by restraining the neurotrophic effect of oleic acid.甲胎蛋白（AFP）通过抑制油酸的神经营养作用来调节血清白蛋白对大脑发育的影响。
Brain Res. 2015 Oct 22;1624:45-58. doi: 10.1016/j.brainres.2015.07.021. Epub 2015 Jul 22.
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Alpha fetoprotein and albumin gene transcripts are detected in distinct cell populations of the brain and kidney of the developing rat.在发育中大鼠的脑和肾的不同细胞群体中检测到甲胎蛋白和白蛋白基因转录本。
Differentiation. 1988 Nov;39(1):59-65. doi: 10.1111/j.1432-0436.1988.tb00081.x.
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Fatty acids bound to alpha-fetoprotein and albumin during rat development.大鼠发育过程中与甲胎蛋白和白蛋白结合的脂肪酸。
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alpha-Fetoprotein and albumin gene expression in brain and other tissues of fetal and adult rats.α-甲胎蛋白和白蛋白基因在胎鼠及成年大鼠脑和其他组织中的表达
Brain Res. 1985 Sep;354(1):49-53. doi: 10.1016/0165-3806(85)90067-7.

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Alpha-fetoprotein (AFP) in granulomatous inflammation of the mouse.小鼠肉芽肿性炎症中的甲胎蛋白（AFP）
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Fetuin as a marker of cortical plate cells in the fetal cow neocortex: a comparison of the distribution of fetuin, alpha 2HS-glycoprotein, alpha-fetoprotein and albumin during early development.胎球蛋白作为胎牛新皮质中皮质板细胞的标志物：早期发育过程中胎球蛋白、α2HS-糖蛋白、甲胎蛋白和白蛋白分布的比较
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