Langrehr D, Newton D, Agoston S
Klin Wochenschr. 1982 Sep 1;60(17):1010-6. doi: 10.1007/BF01716964.
We consider 292 anaphylactoid reactions from the own material (1964-1980) out of two different Departments of anesthesiology to attempt to review the continental epidemiology of this life-threatening adverse drug reaction. We conclude the following: The specialty of this type of adverse reaction is likely to prove a special separating name i.e. "anaphylactoid reaction". The overall frequency can be estimated for 1 : 400-600 in anesthesiology, a preponderance of females may be possible. There is no predictability of the reaction, not even by sophisticated history. But it is possible to avoid the development of severe shock by early diagnosis and immediate full causative therapy. With growing experience in diagnosis and therapy the mortality of anaphylactoid reaction should be irrelevant in the near future.
我们研究了来自两个不同麻醉科的292例由自身物质引起的类过敏反应（1964 - 1980年），试图回顾这种危及生命的药物不良反应的大陆流行病学情况。我们得出以下结论：这种类型的不良反应可能需要一个特殊的独立名称，即“类过敏反应”。在麻醉学中，总体发生率估计为1:400 - 600，女性可能占多数。这种反应无法预测，即使详细询问病史也不行。但通过早期诊断和立即进行全面的病因治疗，可以避免严重休克的发生。随着诊断和治疗经验的增加，类过敏反应的死亡率在不久的将来应该会无关紧要。
