[同种免疫后移植物抗宿主反应的增强。H-2系统血清学定义决定簇的影响]
[Increase of the GvH reaction after alloimmunization. Influence of the serologically defined determinants of the H-2 system].
作者信息
Brock J, Siegl E, Schulze H A
出版信息
Allerg Immunol (Leipz). 1982;28(2):91-6.
GvH reactions were induced in (CBA X C57B1)F1 and (CBA X A)F1 mice with sensitized lymphocytes. Specific sensitization results in an increased GvH reaction, sensitization against third party cells does not influence the GvH reaction. Therefore serologically defined public antigens of the H-2 system play not role in the GvH reaction. The comparison of different numbers of specifically sensitized lymphocytes, lymphocytes sensitized against third party cells, and control lymphocytes for the induction of the GvH reaction leads to the same result.
用致敏淋巴细胞在（CBA×C57B1）F1和（CBA×A）F1小鼠中诱导移植物抗宿主（GvH）反应。特异性致敏会导致GvH反应增强，对第三方细胞的致敏不会影响GvH反应。因此，H-2系统血清学定义的公共抗原在GvH反应中不起作用。比较不同数量的特异性致敏淋巴细胞、对第三方细胞致敏的淋巴细胞以及用于诱导GvH反应的对照淋巴细胞，会得到相同的结果。
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