Börger H W, Schafmayer A, Becker H D
Chir Forum Exp Klin Forsch. 1977 Apr:224-7.
Serum gastrin, serum-GIP and serum insulin levels were measured before and after interposition operation (Henley-Soupault) in 10 patients with severe dumping-syndrome (PGS). The results were compared to those obtained in 10 normal subjects without any gastrointestinal disease. In the PGS pre-operative group there was a significantly lower serum gastrin concentration compared to normals, while the serum-GIP-concentration was significantly higher. After interposition operation all serum-hormone-levels tended towards normal values. There was no difference between the basal serum insulin levels of the three groups. The change in postprandial insulin release was parallel to the serum-GIP-levels. It is concluded that there is a close connection between disturbed release of gastrointestinal hormones and the dumping syndrome.
对10例重度倾倒综合征（PGS）患者在进行间置术（亨利-苏波手术）前后测量血清胃泌素、血清GIP和血清胰岛素水平。将结果与10名无任何胃肠道疾病的正常受试者的结果进行比较。在PGS术前组中，血清胃泌素浓度明显低于正常组，而血清GIP浓度明显更高。间置术后，所有血清激素水平均趋于正常。三组的基础血清胰岛素水平无差异。餐后胰岛素释放的变化与血清GIP水平平行。结论是胃肠道激素释放紊乱与倾倒综合征之间存在密切联系。
