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肺癌手术中的长期生存与治愈

Long-term survival and cure in lung cancer surgery.

作者信息

Sørensen H R

出版信息

Thorac Cardiovasc Surg. 1982 Oct;30(5):292-3. doi: 10.1055/s-2007-1022409.

Abstract

From 1942 to July 1955, 265 lung cancer patients were resected. There were 51 hospital deaths and 214 patients were discharged. All survivors have been followed-up for at least 25 years, and 8 are still alive--one patient 30 years after pneumonectomy. Survival after 5, 10, 15 and 25 years were 32%, 22%, 15%, 10% and 5%, excluding hospital deaths. A survival curve for a Danish population of the same age and sex has been calculated and used for construction of an adjusted survival curve, describing the survival from lung cancer patients divided by survival of general population multiplied by 100. Cure time is obtained when the adjusted survival percentage is constant. This happened 14 years after surgery and no patient with demonstrable lymph node metastasis survived cure time. Cure rate was a little more than 20%. Lung cancer patients can live to be old after either lobectomy or pneumonectomy.

摘要

1942年至1955年7月,对265例肺癌患者实施了切除术。其中51例患者术后在医院死亡,214例患者出院。所有幸存者均接受了至少25年的随访,8人仍然存活——1例患者在肺切除术后30年仍存活。排除医院死亡病例后,5年、10年、15年和25年的生存率分别为32%、22%、15%、10%和5%。已计算出丹麦同年龄和性别人群的生存曲线,并用于构建调整后的生存曲线,即肺癌患者的生存率除以普通人群的生存率再乘以100。当调整后的生存百分比恒定时,即达到治愈时间。这发生在术后14年,且没有可证实有淋巴结转移的患者存活至治愈时间。治愈率略高于20%。肺癌患者在肺叶切除术或全肺切除术后都可以活到高龄。

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