Zhilinskaya I N, Kozeletskaya K N, Stamkulova A A, Golubev D B
Virologie. 1982 Jul-Sep;33(3):237-40.
The genome structure of different A(H1N1) and A(H3N2) influenza virus strains isolated from 1977 to 1980 was analysed by electrophoresis of single-stranded RNA and of the double-stranded RNA obtained by hybridization with complementary RNA of the A/Stavropol 188/79 (H3N2) strain. The differences in genome structure are insignificant within the A(H1N1) subtype, and considerable (involving almost all the 8 RNA fragments) between the two A(H3N2) strains (A/Texas 1/77 and A/Stavropol 188/79). The great differences between the genomes of A(H1N1) and A(H3N2) strains do not exclude certain genetic relationships between these viruses.
通过对单链RNA以及与A/斯塔夫罗波尔188/79(H3N2)毒株互补RNA杂交获得的双链RNA进行电泳,分析了1977年至1980年分离出的不同A(H1N1)和A(H3N2)流感病毒毒株的基因组结构。在A(H1N1)亚型内,基因组结构差异不显著,而在两种A(H3N2)毒株(A/得克萨斯1/77和A/斯塔夫罗波尔188/79)之间差异相当大(几乎涉及所有8个RNA片段)。A(H1N1)和A(H3N2)毒株基因组之间的巨大差异并不排除这些病毒之间存在某些遗传关系。