Cowan M J, Giddens W E, Reichenbach D D
Arch Pathol Lab Med. 1983 Jan;107(1):34-9.
A retrospective study was performed to describe the histologic stages of selective myocardial cell necrosis (SMCN) in nonhuman primates, and to compare the incidence of SMCN in two groups of nonhuman primates. Myocardial tissues taken at the time of autopsy from 50 primates at an experimental center were compared with similar tissues from 50 primates housed in a breeding colony. SMCN was confirmed in 20% of the experimental primates and 30% of the breeding primates, proportions that were not significantly different. The incidence and histologic characteristics of SMCN in nonhuman primates were similar to those described in humans, and resembled the lesion produced in experimental primates by administration of catecholamines of by hypokalemia.
进行了一项回顾性研究，以描述非人类灵长类动物选择性心肌细胞坏死（SMCN）的组织学阶段，并比较两组非人类灵长类动物中SMCN的发生率。将实验中心50只灵长类动物尸检时采集的心肌组织与繁殖群体中50只灵长类动物的类似组织进行比较。在20%的实验灵长类动物和30%的繁殖灵长类动物中证实存在SMCN，这两个比例没有显著差异。非人类灵长类动物中SMCN的发生率和组织学特征与人类中描述的相似，并且类似于通过给予儿茶酚胺或低钾血症在实验灵长类动物中产生的病变。
