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[实验性儿茶酚胺诱导坏死中心肌代谢的药理学调节的当前可能性]

[The current possibilities for the pharmacological regulation of myocardial metabolism in experimental catecholamine-induced necroses].

作者信息

Sysoliatina N A, Artamonova V V

机构信息

Institute of Veterinary Medicine, Agrarian University, Omsk, Russia.

出版信息

Eksp Klin Farmakol. 1998 Jan-Feb;61(1):70-3.

PMID:9575418
Abstract

Catecholamine-induced myocardial necroses have their own peculiarities but the disorders in myocardial metabolism occurring in them do not differ in quality from those encountered in necroses caused by occlusion of the coronaries. Pharmacological regulation of the metabolism of a myocardium damaged by catecholamines may be accomplished by the same drugs which are used in necroses caused by coronary occlusion, but agents with antihypoxic and antioxidant activity are preferable.

摘要

儿茶酚胺诱导的心肌坏死有其自身特点,但其中发生的心肌代谢紊乱在性质上与冠状动脉闭塞所致坏死中遇到的并无不同。对儿茶酚胺损伤的心肌代谢进行药理调节可使用与冠状动脉闭塞所致坏死相同的药物,但具有抗缺氧和抗氧化活性的药物更为可取。

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