Shadrin B P, Khalif I L, Turovtseva V V
Zh Mikrobiol Epidemiol Immunobiol. 1982 Aug(8):63-5.
The content of serum antibodies to E. coli O14 O-antigen in patients with inflammatory diseases of the large intestine was studied in the passive hemagglutination test. These antibodies were detected in 77% of patients with nonspecific ulcerous colitis and in all patients with Crohn's disease; of these, 93.5% had antibody titers of 1:32 and greater, while none of the patients with ulcerous colitis showed such titers. This study has led to the conclusion that the detection of these antibodies in high titers can be one of the criteria for the differential diagnosis of nonspecific ulcerous colitis and Crohn's disease.
在被动血凝试验中研究了大肠炎症性疾病患者血清中抗大肠杆菌O14 O抗原抗体的含量。在77%的非特异性溃疡性结肠炎患者和所有克罗恩病患者中检测到了这些抗体;其中,93.5%的患者抗体滴度为1:32及以上,而溃疡性结肠炎患者中无一例有如此高的滴度。这项研究得出结论,高滴度检测到这些抗体可作为非特异性溃疡性结肠炎和克罗恩病鉴别诊断的标准之一。