Forman D T
Ann Clin Lab Sci. 1982 Nov-Dec;12(6):447-52.
Major contributions have been made in the last few years to the knowledge of the structure, fate and cellular origin of beta-2 microglobulin (B2M); but the question of its function still remains unclear. The concept of B2M being simply a marker of renal physiology seems less satisfactory when reference is made to its relationship to the immunogenetic system. Although assay of B2M cannot be considered as a specific diagnostic tool, it still may be regarded as a useful parameter in monitoring inflammatory, malignant, and auto-immune disease activity.
在过去几年里，人们对β2微球蛋白（B2M）的结构、归宿和细胞起源有了重大认识；但其功能问题仍不清楚。当提及B2M与免疫遗传系统的关系时，认为它仅仅是肾脏生理学标志物的概念似乎不太令人满意。尽管B2M检测不能被视为一种特异性诊断工具，但它仍可被视为监测炎症、恶性和自身免疫性疾病活动的一个有用参数。
