Cox K L, Cannon R A, Ament M E, Phillips H E, Schaffer C B
Dig Dis Sci. 1983 Mar;28(3):225-9. doi: 10.1007/BF01295117.
Seven of 10 patients with anorexia nervosa had ultrasonic and/or biochemical abnormalities of the pancreas. Seven patients had elevated amylase creatinine clearance ratios (greater than 4%), three patients had elevated serum amylase values (greater than 90 units/liter), and three patients had reduced echogenicity of the pancreas. There was no consistent association between presenting abdominal symptoms and abnormal ultrasonic and biochemical studies of the pancreas. After nutritional repletion, all studies reverted to normal. An eleventh patient, who was initially diagnosed as having anorexia nervosa but later found to have an astrocytoma of the medulla, had reduced echogenicity of the pancreas, suggesting malnutrition as the cause of these abnormal pancreatic studies. Pancreatic abnormalities due to protein-calorie malnutrition may be common in anorexia nervosa and must be differentiated from primary pancreatitis.
10名神经性厌食症患者中有7人存在胰腺的超声和/或生化异常。7名患者的淀粉酶肌酐清除率升高（大于4%），3名患者的血清淀粉酶值升高（大于90单位/升），3名患者的胰腺回声性降低。出现的腹部症状与胰腺的超声及生化异常检查之间没有一致的关联。营养补充后，所有检查结果均恢复正常。第11名患者最初被诊断为神经性厌食症，但后来发现患有延髓星形细胞瘤，其胰腺回声性降低，提示这些胰腺异常检查的原因是营养不良。蛋白质 - 热量营养不良导致的胰腺异常在神经性厌食症中可能很常见，必须与原发性胰腺炎相鉴别。
