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海蟾蜍膀胱中含肽神经。

Peptide-containing nerves in the urinary bladder of the toad, Bufo marinus.

作者信息

Gibbins I L

出版信息

Cell Tissue Res. 1983;229(1):137-44. doi: 10.1007/BF00217886.

DOI:10.1007/BF00217886
PMID:6187467
Abstract

The distributions of peptide-containing nerves in the urinary bladder of the toad, Bufo marinus, were studied by means of fluorescence immunohistochemistry of whole-mount preparations. The bundles of smooth muscle in the bladder are well supplied by varicose nerve fibres displaying somatostatin-like immunoreactivity; these fibres probably arise from intrinsic perikarya. The urinary bladder also has a well-developed plexus of nerves containing substance P-like immunoreactive material; these elements probably represent sensory nerves of extrinsic origin. Nerve fibres showing immunoreactivity to vasoactive intestinal polypeptide (VIP) or enkephalin are rare within the urinary bladder of the toad. It is considered unlikely that any of these peptides directly mediates the hyoscine-resistant excitatory response of the smooth muscle to nerve stimulation in the toad bladder.

摘要

采用整装标本荧光免疫组织化学方法，研究了海蟾蜍膀胱中含肽神经的分布情况。膀胱中的平滑肌束由显示生长抑素样免疫反应性的曲张神经纤维充分供应；这些纤维可能起源于内在的神经周核。膀胱还有一个发育良好的含有P物质样免疫反应性物质的神经丛；这些成分可能代表外源性感觉神经。在蟾蜍膀胱内，对血管活性肠肽（VIP）或脑啡肽呈免疫反应性的神经纤维很少见。认为这些肽不太可能直接介导蟾蜍膀胱平滑肌对神经刺激的抗东莨菪碱兴奋反应。

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引用本文的文献

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2
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本文引用的文献

1
Occurrence of somatostatin-like immunoreactivity in some peripheral sympathetic noradrenergic neurons.某些外周交感去甲肾上腺素能神经元中生长抑素样免疫反应性的出现。
Proc Natl Acad Sci U S A. 1977 Aug;74(8):3587-91. doi: 10.1073/pnas.74.8.3587.
2
COMPARATIVE PHYSIOLOGY OF THE VERTEBRATE AUTONOMIC NERVOUS SYSTEM. I. INNERVATION OF THE URINARY BLADDER OF THE TOAD (BUFO MARINUS).脊椎动物自主神经系统的比较生理学。一、蟾蜍（海蟾蜍）膀胱的神经支配。
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Effects of active peptides on the isolated muscle of the human urinary bladder.
蟾蜍（海蟾蜍）大动脉和心脏的肾上腺素能神经元及含肽神经元的神经支配。
Cell Tissue Res. 1986;243(1):171-84. doi: 10.1007/BF00221866.
4
Three-dimensional distribution of substance P-like immunoreactivity in the urinary bladder of rat.大鼠膀胱中P物质样免疫反应性的三维分布
J Neural Transm. 1985;63(3-4):209-22. doi: 10.1007/BF01252026.
活性肽对人膀胱离体肌肉的作用。
Invest Urol. 1981 Jan;18(4):302-4.
4
Origin and distribution of VIP (vasoactive intestinal polypeptide)-nerves in the genito-urinary tract.泌尿生殖道中血管活性肠肽（VIP）神经的起源与分布。
Cell Tissue Res. 1980;205(3):337-47. doi: 10.1007/BF00232276.
5
Enkephalin-immunoreactive nerve fibers in the feline genito-urinary tract.猫泌尿生殖道中脑啡肽免疫反应性神经纤维。
Histochemistry. 1981;72(3):351-5. doi: 10.1007/BF00501777.
6
Vasoactive intestinal polypeptide enhances muscarinic ligand binding in cat submandibular salivary gland.血管活性肠肽增强猫下颌下唾液腺中毒蕈碱配体的结合。
Nature. 1982 Jan 14;295(5845):147-9. doi: 10.1038/295147a0.
7
Immunohistochemical localization of polypeptides in peripheral autonomic nerves using whole mount preparations.使用整装标本对外周自主神经中的多肽进行免疫组织化学定位。
Histochemistry. 1980 Feb;65(2):157-65. doi: 10.1007/BF00493164.
8
Lack of correlation between ultrastructural and pharmacological types of non-adrenergic autonomic nerves.非肾上腺素能自主神经的超微结构类型与药理类型之间缺乏相关性。
Cell Tissue Res. 1982;221(3):551-81. doi: 10.1007/BF00215701.
9
Resistance of adrenergic neurotransmission in the toad heart to adrenoceptor blockade.蟾蜍心脏中肾上腺素能神经传递对肾上腺素能受体阻断的抗性。
Naunyn Schmiedebergs Arch Pharmacol. 1981;317(4):331-8. doi: 10.1007/BF00501315.
10
Evidence for and significance of the projection of VIP neurons from the myenteric plexus to the taenia coli in the guinea pig.豚鼠肌间神经丛中血管活性肠肽（VIP）神经元向结肠带投射的证据及意义。
Gastroenterology. 1981 Jun;80(6):1557-61.