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亚致死剂量γ辐射对发育中大鼠大脑的影响。核酸的合成。

Effects of sublethal doses of gamma radiation on the developing rat brain. synthesis of nucleic acids.

作者信息

Cerda H, Carlsson J, Larsson B, Säfwenberg J O

出版信息

Growth. 1982 Winter;46(4):355-66.

PMID:6187631
Abstract

Newborn rats were irradiated with 60Co gamma rays. Doses of 0, 0.8 or 1.6 Gy were given to the whole body. The body and brain weights, DNA and RNA contents of the brain and 3H-thymidine or H-uridine incorporated by the brain were measured at 5, 10, or 15 days after birth. A dose of 1.6 Gy produced alterations in the brain weight and the DNA and RNA contents of the brain while no clear effects could be detected after 0.8 Gy.

摘要

将新生大鼠用60Coγ射线进行辐照。对其全身给予0、0.8或1.6戈瑞的剂量。在出生后5天、10天或15天测量其体重、脑重、脑中DNA和RNA含量以及脑摄取的3H-胸腺嘧啶核苷或H-尿苷。1.6戈瑞的剂量使脑重以及脑中DNA和RNA含量发生了改变,而0.8戈瑞后未检测到明显影响。

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