Hosokawa T, Cinader B
Immunol Lett. 1983 Jan;6(1):51-7. doi: 10.1016/0165-2478(83)90030-5.
A subpopulation of B-cells becomes sensitized in the 15-week-old SJL mouse, exposed to aggregate-freed rabbit gamma-globulin, which is highly tolerogenic when given to younger animals. This state of activation can only be expressed in collaboration with sensitized T-cells. The sensitized B-cell does not play an important role in the response of the intact 15-week-old SJL mouse, since there are no sensitized T-cells in the sRGG-treated animals.
在15周龄的SJL小鼠中，一部分B细胞会对去除聚集物的兔γ球蛋白产生致敏，这种球蛋白在给予年幼动物时具有高度耐受性。这种激活状态只有在与致敏T细胞协同作用时才能表现出来。致敏的B细胞在完整的15周龄SJL小鼠的反应中并不起重要作用，因为在经sRGG处理的动物中没有致敏T细胞。
