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巨细胞病毒感染的骨髓移植受者及先天性巨细胞病毒病婴儿体内的循环干扰素

Circulating interferon in cytomegalovirus infected bone-marrow-transplant recipients and in infants with congenital cytomegalovirus disease.

作者信息

Rhodes-Feuillette A, Canivet M, Champsaur H, Gluckman E, Mazeron M C, Peries J

出版信息

J Interferon Res. 1983;3(1):45-52. doi: 10.1089/jir.1983.3.45.

DOI:10.1089/jir.1983.3.45
PMID:6188792
Abstract

In a study concerning five CMV-infected bone-marrow-transplant recipients, five congenital CMV diseases and appropriate controls, presence of high levels of circulating interferon (IFN) was demonstrated exclusively during the course of CMV disease. This interferon was predominantly "immune" or gamma interferon (gamma-IFN). These results suggest that during CMV disease the interferon compartment of the immune response is modified.

摘要

在一项针对5名巨细胞病毒(CMV)感染的骨髓移植受者、5例先天性CMV疾病患者及相应对照的研究中,仅在CMV疾病病程中证实存在高水平的循环干扰素(IFN)。这种干扰素主要是“免疫性”的或γ干扰素(γ-IFN)。这些结果表明,在CMV疾病期间,免疫反应的干扰素部分发生了改变。

相似文献

1
Circulating interferon in cytomegalovirus infected bone-marrow-transplant recipients and in infants with congenital cytomegalovirus disease.巨细胞病毒感染的骨髓移植受者及先天性巨细胞病毒病婴儿体内的循环干扰素
J Interferon Res. 1983;3(1):45-52. doi: 10.1089/jir.1983.3.45.
2
Circulating interferon in cytomegalovirus infected bone-marrow-transplant recipients and in infants with congenital cytomegalovirus disease.巨细胞病毒感染的骨髓移植受者及先天性巨细胞病毒病婴儿体内的循环干扰素
J Interferon Res. 1992 May;Spec No:91-8. doi: 10.1089/jir.1992.1992.91.
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[Immunity related to cytomegalovirus after allogenic bone marrow transplantation: role of donor immunity to cytomegalovirus in the incidence of cytomegalovirus infection in recipients].
Rev Fr Transfus Immunohematol. 1984 Jun;27(3):331-6. doi: 10.1016/s0338-4535(84)80173-7.
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IgG-subclass-specific CMV reactivity in bone marrow transplant recipients.骨髓移植受者中针对巨细胞病毒的IgG亚类特异性反应性
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Cytomegalovirus infection and specific cell-mediated immunity after marrow transplant.骨髓移植后的巨细胞病毒感染与特异性细胞介导免疫
J Infect Dis. 1980 Dec;142(6):816-24. doi: 10.1093/infdis/142.6.816.
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Early treatment of CMV infections in allogeneic bone marrow transplant recipients with foscarnet or ganciclovir.使用膦甲酸钠或更昔洛韦对异基因骨髓移植受者的巨细胞病毒感染进行早期治疗。
Bone Marrow Transplant. 1994 Jun;13(6):753-8.
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Cytomegalovirus infection in children with blood diseases.
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Rev Fr Transfus Immunohematol. 1984 Jun;27(3):337-44. doi: 10.1016/s0338-4535(84)80174-9.
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Different kinetics in anti-cytomegalovirus immunity reconstitution evaluated by lymphocyte proliferation and IFN-gamma production in allogeneic and autologous bone marrow transplantation.在同种异体和自体骨髓移植中,通过淋巴细胞增殖和干扰素-γ产生评估的抗巨细胞病毒免疫重建的不同动力学。
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The importance of pre bone marrow transplantation serology in determining subsequent cytomegalovirus infection. An analysis of risk factors.骨髓移植前血清学在确定后续巨细胞病毒感染中的重要性。危险因素分析。
Scand J Infect Dis. 1986;18(3):199-209. doi: 10.3109/00365548609032328.

引用本文的文献

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Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses.先天性全身感染和巨细胞病毒感染中人类新生儿树突状细胞的基因组编程揭示了可塑性和强大的免疫通路生物学反应。
Front Immunol. 2017 Sep 25;8:1146. doi: 10.3389/fimmu.2017.01146. eCollection 2017.
2
Human natural interferon-alpha producing cells.人类天然产生α干扰素的细胞。
Pharmacol Ther. 1993 Oct;60(1):39-62. doi: 10.1016/0163-7258(93)90021-5.
3
Studies on in vitro interferon induction capacity and interferon sensitivity of simian foamy viruses.
猿猴泡沫病毒的体外干扰素诱导能力及干扰素敏感性研究。
Arch Virol. 1987;97(1-2):77-84. doi: 10.1007/BF01310735.