巨细胞病毒感染的骨髓移植受者及先天性巨细胞病毒病婴儿体内的循环干扰素
Circulating interferon in cytomegalovirus infected bone-marrow-transplant recipients and in infants with congenital cytomegalovirus disease.
作者信息
Rhodes-Feuillette A, Canivet M, Champsaur H, Gluckman E, Mazeron M C, Peries J
机构信息
Experimental Oncology Department, U. 107 INSERM, LOI CNRS, Institut de Recherches sur les Maladies du Sang, Hôpital Saint-Louis, Paris.
出版信息
J Interferon Res. 1992 May;Spec No:91-8. doi: 10.1089/jir.1992.1992.91.
In a study concerning five CMV-infected bone-marrow-transplant recipients, five congenital CMV diseases and appropriate controls, presence of high levels of circulating interferon (IFN) was demonstrated exclusively during the course of CMV disease. This interferon was predominantly "immune" or gamma interferon (gamma-IFN). These results suggest that during CMV disease the interferon compartment of the immune response is modified.
在一项针对5名巨细胞病毒（CMV）感染的骨髓移植受者、5例先天性CMV疾病及相应对照的研究中，仅在CMV疾病病程中证实存在高水平的循环干扰素（IFN）。这种干扰素主要是“免疫”干扰素或γ干扰素（γ-IFN）。这些结果表明，在CMV疾病期间，免疫反应的干扰素部分发生了改变。
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