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与外周和脑内稳态功能相关的中枢通路中的生化特异性。

Biochemical specificity in central pathways related to peripheral and intracerebral homeostatic functions.

作者信息

Swanson L W, Hartman B K

出版信息

Neurosci Lett. 1980 Jan;16(1):55-60. doi: 10.1016/0304-3940(80)90100-7.

DOI:10.1016/0304-3940(80)90100-7
PMID:6189002
Abstract

Immunohistochemical and horseradish peroxidase (HRP) studies suggest that oxytocin-stained fibers from the paraventricular nucleus of the hypothalamus (PVH) innervate the locus coeruleus (LC) and dorsal vagal complex (DVC) in the brainstem of the rat, and that adrenergic fibers from the LC and DVC in turn project to the PVH. It is hypothesized that these pathways are directly involved in the integration of neuroendocrine and autonomic responses in the periphery, as well as in the mediation of homeostasis-preserving responses within the CNS itself.

摘要

免疫组织化学和辣根过氧化物酶(HRP)研究表明,来自大鼠下丘脑室旁核(PVH)的催产素染色纤维支配脑干中的蓝斑(LC)和迷走背核复合体(DVC),并且来自LC和DVC的肾上腺素能纤维反过来投射到PVH。据推测,这些通路直接参与外周神经内分泌和自主反应的整合,以及中枢神经系统自身内维持内环境稳定反应的介导。

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