Hoshi H, Nakayama S, Kodama T, Jinnouchi S, Nishikawa K, Wakuta Y, Kakitsubata Y, Kusuhara T, Watanabe K
Radioisotopes. 1983 Jan;32(1):13-7.
Serum ferritin levels were studied in 264 patients who were consisted of 153 patients with various malignant neoplasms and 111 patients with various benign diseases. Positive rate of serum ferritin in all patients with malignant neoplasms was 35%. Hepatomas and pulmonary cancer showed relatively high positive rate, respectively 65% and 42%. In patients with benign diseases, hepatic diseases showed the high positive rate (52%) and the other benign diseases was low positive rate (11%). The relationship between serum ferritin and alpha-feto-protein in patients with hepatomas and other liver diseases was low. And the relationship between serum ferritin and CEA (carcinoembryonic antigen) in patients with malignant neoplasms of gastrointestinal tract was also low. It seemed that the measurement of serum ferritin levels will be of low value in the differentiation of the patients with malignant neoplasms.
对264例患者的血清铁蛋白水平进行了研究,其中包括153例患有各种恶性肿瘤的患者和111例患有各种良性疾病的患者。所有恶性肿瘤患者的血清铁蛋白阳性率为35%。肝癌和肺癌的阳性率相对较高,分别为65%和42%。在良性疾病患者中,肝脏疾病的阳性率较高(52%),其他良性疾病的阳性率较低(11%)。肝癌和其他肝脏疾病患者血清铁蛋白与甲胎蛋白之间的关系较弱。胃肠道恶性肿瘤患者血清铁蛋白与癌胚抗原(CEA)之间的关系也较弱。似乎血清铁蛋白水平的测定在恶性肿瘤患者的鉴别诊断中价值不大。