Sass M, Jao W, Horn T, Keh P C
Ultrastruct Pathol. 1983 Jan;4(1):67-73. doi: 10.3109/01913128309140573.
Primary mediastinal yolk sac tumor is rare. In this report, a case of a 32-year-old male with a mediastinal yolk sac tumor was studied by light, electron, and immunofluorescent microscopy. A positive immunofluorescent reaction to alpha-fetoprotein (AFP) correlated with the PAS-positive hyaline globules and electron-dense deposits seen in intracellular and extracellular locations. Serum AFP is a useful tumor marker for monitoring the results of therapy. Review of the literature indicates that the prognosis for patients with yolk sac tumor is generally poor.
原发性纵隔卵黄囊瘤很罕见。在本报告中，对一例32岁患有纵隔卵黄囊瘤的男性患者进行了光镜、电镜和免疫荧光显微镜检查。对甲胎蛋白（AFP）的阳性免疫荧光反应与在细胞内和细胞外位置所见的PAS阳性透明小球及电子致密沉积物相关。血清AFP是监测治疗结果的有用肿瘤标志物。文献回顾表明，卵黄囊瘤患者的预后通常较差。
