Mukai K, Adams W R
Am J Surg Pathol. 1979 Feb;3(1):77-83. doi: 10.1097/00000478-197902000-00009.
A case of yolk sac tumor of the anterior mediastinum was studied by light and electron microscopy and found to have characteristic patterns which were similar to a neoplasm of gonadal origin. These findings, in addition to the immunohistochemical identification of alpha-fetoprotein in the tumor, indicated that the neoplasm was germ cell in origin. A brief review of previously reported cases is included. Prognosis of the patients with yolk sac tumor of the anterior mediastinum was generally dismal; however, those patients with tumors incidentally found but completely excised survived without evidence of reucrrence.
对一例前纵隔卵黄囊瘤进行了光镜和电镜研究，发现其具有与性腺起源肿瘤相似的特征性模式。这些发现，再加上肿瘤中α-甲胎蛋白的免疫组化鉴定，表明该肿瘤起源于生殖细胞。文中还简要回顾了先前报道的病例。前纵隔卵黄囊瘤患者的预后通常不佳；然而，那些偶然发现但完全切除肿瘤的患者存活下来，且无复发迹象。
