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血小板浓缩物制备、体外储存及冷冻保存过程中β-血小板球蛋白的释放

Release of beta-thromboglobulin during the preparation, in vitro storage and cryopreservation of platelet concentrates.

作者信息

Taylor M A

出版信息

J Clin Pathol. 1983 Jul;36(7):811-5. doi: 10.1136/jcp.36.7.811.

Abstract

Beta-thromboglobulin is a platelet specific protein which is released from platelets during the platelet release reaction. The amount of beta-thromboglobulin released during various conditions of in vitro storage, including cryopreservation, was compared. The results suggest the measurement of beta-thromboglobulin is unlikely to be of use as a quality control assay for monitoring the in vitro viability of stored platelets.

摘要

β-血小板球蛋白是一种血小板特异性蛋白,在血小板释放反应过程中从血小板中释放出来。对包括冷冻保存在内的各种体外储存条件下释放的β-血小板球蛋白量进行了比较。结果表明,测量β-血小板球蛋白不太可能用作监测储存血小板体外活力的质量控制检测方法。

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In vitro assessment of platelet damage during rotator storage.
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本文引用的文献

8
An enzymatic method to determine damage in human platelets.一种测定人血小板损伤的酶法。
Proc Soc Exp Biol Med. 1967 Jun;125(2):643-5. doi: 10.3181/00379727-125-32168.
10
Platelet preservation--what temperature? A rationale for strategy.血小板保存——何种温度?策略依据。
Transfusion. 1974 Jul-Aug;14(4):328-30. doi: 10.1111/j.1537-2995.1974.tb04540.x.

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