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Isolation and characterization of three cloned fragments of human DNA coding for tRNAs and small nuclear RNA U1.

作者信息

Buckland R A, Cooke H J, Roy K L, Dahlberg J E, Lund E

出版信息

Gene. 1983 May-Jun;22(2-3):211-7. doi: 10.1016/0378-1119(83)90105-1.

DOI:10.1016/0378-1119(83)90105-1
PMID:6192042
Abstract

Employing a human fetal liver library in lambda Charon 4A phage vector, we have isolated and characterized three clones of human DNA containing genes for tRNAs. One clone contains at least three tRNA genes (tRNALys, tRNAGln and tRNALeu) within 2 kb of each other. The other two clones contain two different single genes for tRNAAsn. One of these latter two DNAs also contains a gene for U1 small nuclear RNA.

摘要

相似文献

1
Isolation and characterization of three cloned fragments of human DNA coding for tRNAs and small nuclear RNA U1.
Gene. 1983 May-Jun;22(2-3):211-7. doi: 10.1016/0378-1119(83)90105-1.
2
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Reverse-transcribed pseudogenes of U1 small nuclear RNA presumably amplified in the rat genome together with the flanking region.U1小核RNA的逆转录假基因可能与侧翼区域一起在大鼠基因组中扩增。
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引用本文的文献

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Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3.围绕人类染色体16p13.3上的家族性地中海热基因座构建一个约700千碱基的转录图谱。
Genome Res. 1998 Nov;8(11):1172-91. doi: 10.1101/gr.8.11.1172.
2
Human U1 RNA genes contain an unusually sensitive nuclease S1 cleavage site within the conserved 3' flanking region.人类U1 RNA基因在保守的3'侧翼区域内含有一个异常敏感的核酸酶S1切割位点。
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7288-92. doi: 10.1073/pnas.81.23.7288.
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Clustered genes for human U2 RNA.
人类U2 RNA的成簇基因。
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Mol Cell Biol. 1983 Dec;3(12):2211-20. doi: 10.1128/mcb.3.12.2211-2220.1983.
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The nucleotide sequences of two human 5S rRNA pseudogenes.两个人类5S rRNA假基因的核苷酸序列。
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Analysis of a sea urchin gene cluster coding for the small nuclear U7 RNA, a rare RNA species implicated in the 3' editing of histone precursor mRNAs.对编码小核U7 RNA的海胆基因簇的分析,U7 RNA是一种罕见的RNA,与组蛋白前体mRNA的3' 端编辑有关。
Proc Natl Acad Sci U S A. 1986 May;83(10):3243-7. doi: 10.1073/pnas.83.10.3243.
7
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Am J Hum Genet. 1989 Aug;45(2):283-95.