药物性鼻炎。一项实验性组织病理学和组织化学研究。
Rhinitis medicamentosa. An experimental histopathological and histochemical study.
作者信息
Elwany S S, Stephanos W M
出版信息
ORL J Otorhinolaryngol Relat Spec. 1983;45(4):187-94. doi: 10.1159/000275642.
PMID:6192384
Abstract
The deleterious effects of decongestant drops on the respiratory nasal mucosa of guinea pigs were studied histopathologically and histochemically. The histopathological changes included: initial goblet cell hyperplasia, squamous metaplasia, increased vascularity, oedema of the corium, mononuclear cellular infiltration and glandular hyperplasia. The histochemical changes indicated: increased secretory activity, increased phagocytic activity as well as disturbance of the vasomotor response.
摘要
通过组织病理学和组织化学方法研究了减充血剂滴鼻剂对豚鼠呼吸道鼻黏膜的有害影响。组织病理学变化包括：初期杯状细胞增生、鳞状化生、血管增多、真皮水肿、单核细胞浸润和腺体增生。组织化学变化表明：分泌活性增加、吞噬活性增加以及血管运动反应紊乱。
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