Valiathan M S, Sankarkumar R, Balakrishnan K G, Mohansingh M P
Thorax. 1983 Jun;38(6):421-7. doi: 10.1136/thx.38.6.421.
Endomyocardial fibrosis is a fatal disease of obscure aetiology which is notably prevalent in Uganda, Brazil, Kerala State in India, and certain other parts of the world. The main disability in the disease results from fibrotic obliteration of ventricular chambers and insufficiency of the mitral and tricuspid valves. The poor response to medical treatment and the bleak prognosis of the patients led to the introduction of endocardiectomy and replacement of the atrioventricular valves as a palliative procedure by Dubost and colleagues. The present report on the early results in 17 patients from Kerala State would support the continued use of this palliative procedure in endomyocardial fibrosis with severe disability.
心内膜心肌纤维化是一种病因不明的致命疾病,在乌干达、巴西、印度喀拉拉邦以及世界其他一些地区尤为普遍。该疾病的主要致残原因是心室腔的纤维化闭塞以及二尖瓣和三尖瓣功能不全。由于药物治疗效果不佳且患者预后不良,Dubost及其同事引入了心内膜切除术和房室瓣膜置换术作为一种姑息性手术。本报告关于喀拉拉邦17例患者的早期结果,将支持在重度致残的心内膜心肌纤维化患者中继续使用这种姑息性手术。