Whitelaw M N, Gigli P, Pepper J R
Thorac Cardiovasc Surg. 1983 Jun;31(3):139-41. doi: 10.1055/s-2007-1021963.
Broncho-alveolar lavage was performed on normal and transplanted lungs of dogs that had received unilateral autografts or allografts without immuno-suppression. Differential cell counts were performed on the lavage fluid. Allografts showed a progressive rise in the proportion of neutrophils from the operated lung compared to the unoperated lung. Rejection in the operated lung was subsequently confirmed histologically. Autografted lungs showed no differences in differential cell counts from the unoperated side. Differential cell counts on broncho-alveolar lavage specimens may be useful as an indication of lung allograft rejection.
对接受了单侧自体移植或同种异体移植且未进行免疫抑制的犬的正常肺和移植肺进行支气管肺泡灌洗。对灌洗液进行细胞分类计数。与未手术侧肺相比，同种异体移植的手术侧肺中中性粒细胞比例呈逐渐上升趋势。随后经组织学证实手术侧肺发生了排斥反应。自体移植肺在细胞分类计数上与未手术侧无差异。支气管肺泡灌洗标本的细胞分类计数可能有助于作为肺同种异体移植排斥反应的一个指标。
