Brunswick D J, Frazer A, Mendels J, Ramsey T A
Neuropsychobiology. 1978;4(2):121-7. doi: 10.1159/000117626.
The relationship between the lithium ratio (ratio of lithium in blood cells to that in plasma) and plasma lithium concentration was examined in a group of male inpatients taking lithium carbonate for affective disorders. The lithium ratio was found to increase in the majority of these patients as plasma lithium concentration increased. However, the magnitude of variation of the lithium ratio with plasma lithium concentration observed in these patients is not sufficient to seriously affect the value of determining the lithium ratio in the clinical situation.
在一组因情感障碍而服用碳酸锂的男性住院患者中,研究了锂比率(血细胞中锂与血浆中锂的比率)与血浆锂浓度之间的关系。结果发现,随着血浆锂浓度的升高,这些患者中的大多数锂比率也会升高。然而,在这些患者中观察到的锂比率随血浆锂浓度的变化幅度,不足以严重影响在临床情况下测定锂比率的价值。