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服用碳酸锂患者血浆与红细胞锂水平的关系。

The relationship of plasma to erythrocyte lithium levels in patients taking lithium carbonate.

作者信息

Lee C R, Hill S E, Dimitrakoudi M, Jenner F A, Pollitt R J

出版信息

Br J Psychiatry. 1975 Dec;127:596-8. doi: 10.1192/bjp.127.6.596.

DOI:10.1192/bjp.127.6.596
PMID:1201455
Abstract

Plasma and erythrocyte lithium levels have been determined repeatedly in twelve patients taking lithium carbonate for affective disorders. In any individual the plot of the plasma lithium level against erythrocyte/plasma ratio is linear, but the ratio can either increase or decrease with increasing plasma lithium concentration. Erythrocyte/plasma ratio is an unsound basis for comparing individual responses to lithium.

摘要

对12名服用碳酸锂治疗情感障碍的患者反复测定了血浆和红细胞锂水平。对于任何个体而言，血浆锂水平与红细胞/血浆比值的关系图呈线性，但该比值可能随血浆锂浓度升高而增加或降低。红细胞/血浆比值并非比较个体对锂反应的可靠依据。

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