[Morphologic and functional criteria of preleukemia].

Investigations performed in 32 patients with haemopoietic dysplasia which are transformed into acute leukemia in a number of observations are presented with respect to their morphological, cytogenetic and immunological peculiarities. It could be shown that the presence of pathological forms of mitosis, instability of the karyotype, and auto-immune disturbances will provide favourable prerequisites for the development of leukemia.