Shively J A
Ann Clin Lab Sci. 1980 Mar-Apr;10(2):95-9.
Preleukemia, which can only be diagnosed retrospectively with certainty, presents multiple findings and clinical data which contribute to a pattern recognition process. The development of cytogenetic and marrow culture studies has not only provided additional criteria for diagnosis but also better indices of prognosis. Preleukemia can be considered to be an early expression of neoplastic disease that merges into smoldering leukemia and progresses to acute leukemia. However, in the prospective evaluation of a patient, the term hemopoietic dysplasia should be used since there are no criteria to predict the outcome in an individual case.
白血病前期只能通过回顾性分析才能确诊，它具有多种表现及临床数据，有助于进行模式识别。细胞遗传学和骨髓培养研究的发展不仅为诊断提供了更多标准，还提供了更好的预后指标。白血病前期可被视为肿瘤性疾病的早期表现，它会发展为冒烟型白血病，并进一步进展为急性白血病。然而，在对患者进行前瞻性评估时，应使用造血发育异常这一术语，因为尚无标准可预测个体病例的预后。
