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Monocyte markers and the common acute lymphoblastic leukemia antigen on chronic lymphocytic leukemia cells.

作者信息

Ligler F S, Schlam M L, Curley R, Brodsky I, Benzel J E

出版信息

Am J Hematol. 1983 Dec;15(4):335-42. doi: 10.1002/ajh.2830150404.

DOI:10.1002/ajh.2830150404
PMID:6196965
Abstract

The mononuclear cells from 42 patients with chronic lymphocytic leukemia (CLL) were analyzed for surface markers using monoclonal antibodies and flow cytofluorimetry. All 42 CLLs were Ig+HLA.DR+OKT3-OKT4-OKT6-OKT8- and monoclonal with respect to light chain type. Thirty of the 42 tumors expressed the common acute lymphocytic leukemia antigen, and cells from 18 leukemias stained with the antibodies OKM1 and 63D3, which are specific for different antigens characteristic of myeloid cells. Eight of the leukemias failed to stain with PI153, which has been reported to recognize all B-cell CLLs.

摘要

相似文献

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Monocyte markers and the common acute lymphoblastic leukemia antigen on chronic lymphocytic leukemia cells.
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N Engl J Med. 1981 May 28;304(22):1319-23. doi: 10.1056/NEJM198105283042202.

引用本文的文献

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Different reactivity of monoclonal antibodies against common acute lymphoblastic leukaemia antigen (CD10).针对常见急性淋巴细胞白血病抗原(CD10)的单克隆抗体的不同反应性。
J Clin Pathol. 1987 May;40(5):490-3. doi: 10.1136/jcp.40.5.490.
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Characterization of chronic lymphocytic leukemia (CLL) cells with low density of surface membrane bound immunoglobulins (smIg).具有低密度表面膜结合免疫球蛋白(smIg)的慢性淋巴细胞白血病(CLL)细胞的特征分析
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