Branch A D, Robertson H D
Science. 1984 Feb 3;223(4635):450-5. doi: 10.1126/science.6197756.
Experimental data concerning viroid-specific nucleic acids accumulating in tomato plants establish, together with earlier studies, the major features of a replication cycle for viroid RNA in plant cells. Many features of this pathway, which involves multimeric strands of both polarities, may be shared by other small infectious RNA's including certain satellite RNA's and "virusoid" RNA's which replicate in conjunction with conventional plant viruses. The presence, in host plans, of an elaborate machinery for replicating these disease agents suggests a role for endogenous small RNA's in cellular development.
关于在番茄植株中积累的类病毒特异性核酸的实验数据，与早期研究一起，确立了植物细胞中类病毒RNA复制周期的主要特征。这条涉及两种极性多聚体链的途径的许多特征，可能为其他小的感染性RNA所共有，包括某些卫星RNA和与传统植物病毒一起复制的“拟病毒”RNA。宿主植物中存在用于复制这些致病因子的精密机制，这表明内源性小RNA在细胞发育中发挥作用。
