鞘内注射β-内啡肽后癌症患者的行为变化。
Behavioral change in a cancer patient following intrathecal beta-endorphin administration.
作者信息
Pickar D, Dubois M, Cohen M R
出版信息
Am J Psychiatry. 1984 Jan;141(1):103-4. doi: 10.1176/ajp.141.1.103.
PMID:6197891
Abstract
A patient with a disseminated malignancy received 3 mg of synthetic beta-endorphin administered intrathecally by lumbar puncture. A marked behavioral syndrome characterized by confusion, hypomanic/manic behavior, and psychosis followed drug administration and persisted for more than 2 days.
摘要
一名患有播散性恶性肿瘤的患者通过腰椎穿刺鞘内注射了3毫克合成β-内啡肽。用药后出现了以意识模糊、轻躁狂/躁狂行为和精神病为特征的明显行为综合征，且持续了两天以上。
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